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Search Results for " heparan sulfate "

7

Compounds

Cat No. Product Name Synonyms Targets
T19355 Heparan Sulfate FGFR , Wnt/beta-catenin , Endogenous Metabolite
Heparan Sulfate, a complex and linear polysaccharide, forms a component of glycoproteins called heparan sulfate proteoglycans, abundantly expressed on the cell surface and within the extracellular matrix.
T16380 OGT 2115 Others
OGT 2115 is an inhibitor of heparanase (IC50 = 0.4 µM), an enzyme that cleaves heparan sulfate into glucuronic acid (GlcUA) and N-acetylglucosamine (GlcNAc). OGT 2115 also showed antiangiogenic properties (IC50=1 μM).
T69224 Hemisurfen
Hemisurfen is a small molecule, surfen derivative with heparan sulfate antagonist properties.
T36111 L-Iduronic acid sodium salt
L-Iduronic acid sodium salt is a monosaccharide that is an important component of glycosaminoglycans (GAGs) such as heparin, heparan sulfate, and dermatan sulfate.
T81940 Lepunafusp alfa JR-171
Lepunafusp alfa (JR-171) is a blood-brain barrier-penetrating fusion protein comprising J-Brain Cargo and α-L-iduronidase (IDUA), a lysosomal enzyme. This compound effectively lowers the levels of heparan sulfate (HS) an...
TP1555 Fibronectin Active Fragment Control
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins.In addition to integrins, fibronectin also binds extracellular matrix ...
T81573 Pabinafusp alfa JR-141
Pabinafusp alfa (JR-141), a transferrin receptor-targeting antibody fusing Iduronate 2-sulfatase with an anti-human transferrin receptor antibody, penetrates the blood-brain barrier and inhibits heparan sulfate (HS) accu...
TargetMol